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Selenium sulfide (7446-34-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9021265

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Positive, Male, Rats
View
  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Negative, Male, Mice
View
  • Negative, Male, Mice
View
  • Positive, Female, Mice
View
  • Negative, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Selenium sulfide (7446-34-6).
Rodent Cytogenetics
CA SCE
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Selenium sulfide (7446-34-6).
Micronucleus - Mice
View
  • Male: Negative
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Selenium sulfide (7446-34-6).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Selenium sulfide (7446-34-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Selenium sulfide (7446-34-6).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Selenium sulfide (7446-34-6).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. Selenium sulfide (7446-34-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-194 Bioassay of Selenium Sulfide (Gavage) for Possible Carcinogenicity (CASRN 7446-34-6)
TR-197 Bioassay of Selenium Sulfide (Dermal Study) for Possible Carcinogenicity (CASRN 7446-34-6)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
Myhr, B. and Caspary, W. Chemical mutagenesis at the TK locus in L5178Y mouse lymphoma cells. I. Results for 31 coded compounds in the National Toxicology Program. Environ. Molec. Mutagen. Vol. 18 (1991) 51-83
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
Loveday, K.S., Anderson, B.E., Resnick, M.A., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro V: Results with 46 chemicals Environ. Molec. Mutagen. Vol. 16 (1990) 272-303
Shelby, M.D. and Witt, K.L. Comparision of Results from Mouse Bone Marrow Chromosome Aberration and Micronucleus Test 25 (1995) Vol. 25, 1995 302-313

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Selenium Sulfide (7446-34-6) in Male F344 Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Selenium Sulfide (7446-34-6) in Female F344 Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Selenium Sulfide (7446-34-6) in Male B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Selenium Sulfide (7446-34-6) in Female B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Selenium Sulfide (7446-34-6) in Male Swiss Mice Exposed via Topical Application
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Selenium Sulfide (7446-34-6) in Female Swiss Mice Exposed via Topical Application
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Selenium Sulfide (7446-34-6) in Micronucleus Study 505251 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Selenium Sulfide (7446-34-6) in Micronucleus Study A25043 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Selenium Sulfide in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 029359
Summary Data

DTT Data Collections