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Black cohoshes

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Black cohoshes.
Micronucleus - Rats
View
  • Female: Positive
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Black cohoshes.
Micronucleus - Mice
View
  • Female: Positive
View
  • Female: Positive
View
  • Female: Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Black cohoshes.
Bacterial Mutagenicity
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  • Negative
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  • Negative
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  • Negative
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  • Equivocal
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  • Negative
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  • Negative
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  • Negative

Citation Information

NTP. Black cohoshes. Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

Mercado-Feliciano M, Cora MC, Witt KL, Granville CA, Hejtmancik MR, Fomby L, Knostman KA, Ryan MJ, Newbold R, Smith C, Foster PM, Vallant MK, Stout MD. Anethanolic extract of black cohosh causes hematological changes but not estrogenic effects in female rodents. Toxicol Appl Pharmacol. 2012 Sep 1;263(2):138-47. doi:10.1016/j.taap.2012.05.022. Epub 2012 Jun 9.
Mercado-Feliciano M, Cora MC, Witt KL, Granville CA, Hejtmancik MR, Fomby L, Knostman KA, Ryan MJ, Newbold R, Smith C, Foster PM, Vallant MK, Stout MD. Anethanolic extract of black cohosh causes hematological changes but not estrogenic effects in female rodents. Toxicol Appl Pharmacol. 2012 Sep 1;263(2):138-47. doi:10.1016/j.taap.2012.05.022. Epub 2012 Jun 9.

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Actaea racemosa (Black Cohosh) XRM in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058V
Summary Data
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058 in Wistar Han Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058B in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058C in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058E in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Black Cohosh (BCE_3012781) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058Y
Summary Data
Genetic Toxicity Evaluation of Black Cohosh (BCE_BCO2.5-A2401090310) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058X
Summary Data
Genetic Toxicity Evaluation of Black Cohosh Extract (BCE2) (BCE_TP20141210-R) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058Z
Summary Data
Genetic Toxicity Evaluation of Black Cohosh in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A13815
Summary Data
Genetic Toxicity Evaluation of Black Cohosh in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058D
Summary Data
Genetic Toxicity Evaluation of Black Cohosh Extract (BCE3) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058W
Summary Data