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TR-311: Tetrachloroethylene (127-18-4)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Male, Rats
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  • Some Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Clear Evidence, Male, Mice
View
  • Clear Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-311: Tetrachloroethylene (127-18-4).
Mammalian Cell Mutagenicity
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  • Equivocal
View
  • Equivocal
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  • Equivocal
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-311: Tetrachloroethylene (127-18-4).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-311: Tetrachloroethylene (127-18-4).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-311: Tetrachloroethylene (127-18-4).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. TR-311: Tetrachloroethylene (127-18-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-311 Toxicology and Carcinogenesis Studies of Tetrachloroethylene (Perchloroethylene) (CASRN 127-18-4) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Tetrachloroethylene (127-18-4) in Male F344 Rats via Whole Body Respiratory Exposure
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Tetrachloroethylene (127-18-4) in Female F344 Rats via Whole Body Respiratory Exposure
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Tetrachloroethylene (127-18-4) in Male B6C3F1 Mice via Whole Body Respiratory Exposure
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Tetrachloroethylene (127-18-4) in Female B6C3F1 Mice via Whole Body Respiratory Exposure
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Tetrachloroethylene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 269792
Summary Data