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TR-329: 1,2-Epoxybutane (106-88-7)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Male, Rats
View
  • Equivocal Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Male, Mice
View
  • No Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-329: 1,2-Epoxybutane (106-88-7).
Mammalian Cell Mutagenicity
View
  • Positive
View
  • Positive
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-329: 1,2-Epoxybutane (106-88-7).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-329: 1,2-Epoxybutane (106-88-7).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-329: 1,2-Epoxybutane (106-88-7).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. TR-329: 1,2-Epoxybutane (106-88-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-329 Toxicology and Carcinogenesis Studies of 1,2-Epoxybutane (CASRN 106-88-7) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Epoxybutane (106-88-7) in Male F344 Rats via Whole Body Respiratory Exposure
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Epoxybutane (106-88-7) in Female F344 Rats via Whole Body Respiratory Exposure
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Epoxybutane (106-88-7) in Male B6C3F1 Mice via Whole Body Respiratory Exposure
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Epoxybutane (106-88-7) in Female B6C3F1 Mice via Whole Body Respiratory Exposure
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 1,2-Epoxybutane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 970583
Summary Data