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TR-506: Acrylonitrile (107-13-1)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-506: Acrylonitrile (107-13-1).
Micronucleus - Mice
View
  • Female: Negative
View
  • Male: Negative
    Female: Negative
View
  • Female: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-506: Acrylonitrile (107-13-1).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-506: Acrylonitrile (107-13-1).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-506: Acrylonitrile (107-13-1).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-506: Acrylonitrile (107-13-1).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. TR-506: Acrylonitrile (107-13-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-506 Toxicology and Carcinogenesis Studies of Acrylonitrile (CASRN 107-13-1) in B6C3F1 Mice (Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C50215B) of Acrylonitrile (107-13-1) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C50215B) of Acrylonitrile (107-13-1) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Acrylonitrile (107-13-1) in Micronucleus Study A56933 in B6C3F1 Mice
Genetic Toxicity Evaluation of Acrylonitrile (107-13-1) in Micronucleus Study A69991 in B6C3F1 Mice
Genetic Toxicity Evaluation of Acrylonitrile (107-13-1) in Micronucleus Study A92525 in B6C3F1 Mice
Genetic Toxicity Evaluation of Acrylonitrile in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 198018
Summary Data