Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit  cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Diglycidyl resorcinol ether (101-90-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2020470

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Positive, Male, Rats
View
  • Positive, Male, Rats
View
  • Positive, Female, Rats
View
  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Positive, Male, Mice
View
  • Positive, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Diglycidyl resorcinol ether (101-90-6).
Rodent Cytogenetics
CA SCE
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Diglycidyl resorcinol ether (101-90-6).
Micronucleus - Mice
View
  • Male: Positive
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Diglycidyl resorcinol ether (101-90-6).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Diglycidyl resorcinol ether (101-90-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Diglycidyl resorcinol ether (101-90-6).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Diglycidyl resorcinol ether (101-90-6).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. Diglycidyl resorcinol ether (101-90-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-257 Toxicology and Carcinogenesis Studies of Diglycidyl Resorcinol Ether (Technical Grade) (CASRN 101-90-6) In F344/N Rats and B6C3F1 Mice (Gavage Studies)
Canter, D.A., Zeiger, E., Haworth, S., Lawlor, T., Mortelmans, K., and Speck, W. Comparative mutagenicity of aliphatic epoxides in Salmonella Mutation Res. Vol. 172 (1986) 105-138
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Male F344 Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Male F344 Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Female F344 Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Female F344 Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Male B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Female B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Micronucleus Study 367536 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Micronucleus Study A56274 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Diglycidyl Resorcinol Ether (DGRE) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 493700
Summary Data

DTT Data Collections