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2-Chloroethanol (107-07-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1021877

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Male, Rats
View
  • No Evidence, Female, Rats

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to 2-Chloroethanol (107-07-3).
Rodent Cytogenetics
CA SCE
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2-Chloroethanol (107-07-3).
Micronucleus - Mice
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to 2-Chloroethanol (107-07-3).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2-Chloroethanol (107-07-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to 2-Chloroethanol (107-07-3).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2-Chloroethanol (107-07-3).
Bacterial Mutagenicity
View
  • Positive
View
  • Positive
View
  • Positive

Citation Information

NTP. 2-Chloroethanol (107-07-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-275 Toxicology and Carcinogenesis Studies of 2-Chloroethanol (Ethylene Chlorohydrin) (CASRN 107-07-3) in F344/N Rats and Swiss CD-1 Mice (Dermal Studies)
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Ivett, J.L., Brown, B.M., Rodgers, C., Anderson, B.E., Resnick, M.A., Zeiger, E. Chromosomal aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro IV: Results for 15 chemicals Environ. Molec. Mutagen. Vol. 14 (1989) 165-187

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of 2-Chloroethanol (Ethylene Chlorohydrin) (107-07-3) in Male F344 Rats Exposed via Topical Application
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 2-Chloroethanol (Ethylene Chlorohydrin) (107-07-3) in Female F344 Rats Exposed via Topical Application
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 2-Chloroethanol (Ethylene Chlorohydrin) (107-07-3) in Micronucleus Study 666681 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2-Chloroethanol (Ethylene Chlorohydrin) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 051370
Summary Data
Genetic Toxicity Evaluation of 2-Chloroethanol (Ethylene Chlorohydrin) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 052370
Summary Data
Genetic Toxicity Evaluation of 2-Chloroethanol (Ethylene Chlorohydrin) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 552370
Summary Data

DTT Data Collections