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1,2-Dibromo-2,4-dicyanobutane (35691-65-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3024944


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 1,2-Dibromo-2,4-dicyanobutane (35691-65-7).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 1,2-Dibromo-2,4-dicyanobutane (35691-65-7).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. 1,2-Dibromo-2,4-dicyanobutane (35691-65-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-555 Toxicology and Carcinogenesis Studies of 1,2-Dibromo-2,4-dicyanobutane (CASRN 35691-65-7) in F344/N Rats and B6C3F1 Mice (Dermal Studies)

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C97003B) of 1,2-Dibromo-2,4-dicyanobutane (35691-65-7) in F344/N Rats Exposed via Topical Application
3-Month Evaluation of the Toxicity (C97003C) of 1,2-Dibromo-2-4-dicyanobutane (35691-65-7) in F344 Rats Exposed via Topical Application. NTP Special Study
2-Week Evaluation of the Toxicity (C97003) of 1,2-Dibromo-2,4-dicyanobutane (35691-65-7) in B6C3F1 Mice Exposed via Gavage
2-Week Evaluation of the Toxicity (C97003B) of 1,2-Dibromo-2,4-dicyanobutane (35691-65-7) in B6C3F1 Mice Exposed via Topical Application
3-Month Evaluation of the Toxicity (C97003C) of 1,2-Dibromo-2-4-dicyanobutane (35691-65-7) in B6C3F1 Mice Exposed via Topical Application. NTP Special Study
3-Month Evaluation of the Toxicity (C97003C) of 1,2-Dibromo-2,4-dicyanobutane (35691-65-7) in F344/N Rats Exposed via Topical Application
3-Month Evaluation of the Toxicity (C97003C) of 1,2-Dibromo-2,4-dicyanobutane (35691-65-7) in B6C3F1 Mice Exposed via Topical Application
Evaluation of the Chronic Toxicity and Carcinogenicity (C97003D) of 1,2-Dibromo-2,4-dicyanobutane (35691-65-7) in F344/N Rats Exposed via Topical Application
Evaluation of the Chronic Toxicity and Carcinogenicity (C97003D) of 1,2-Dibromo-2,4-dicyanobutane (35691-65-7) in B6C3F1 Mice Exposed via Topical Application

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 1,2-Dibromo-2,4-dicyanobutane (35691-65-7) in Micronucleus Study A65692 in B6C3F1 Mice
Genetic Toxicity Evaluation of 1,2-Dibromo-2,4-dicyanobutane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A11889
Summary Data
Genetic Toxicity Evaluation of 1,2-Dibromo-2,4-dicyanobutane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A92777
Summary Data