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TR-475: Tetrahydrofuran (109-99-9)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • Some Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to TR-475: Tetrahydrofuran (109-99-9).
Rodent Cytogenetics
CA
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-475: Tetrahydrofuran (109-99-9).
Micronucleus - Mice
View
  • Male: Equivocal
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-475: Tetrahydrofuran (109-99-9).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-475: Tetrahydrofuran (109-99-9).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-475: Tetrahydrofuran (109-99-9).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. TR-475: Tetrahydrofuran (109-99-9). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-475 Toxicology and Carcinogenesis Studies of Tetrahydrofuran (CASRN 109-99-9) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C60560B) of Tetrahydrofuran (109-99-9) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C60560B) of Tetrahydrofuran (109-99-9) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C60560C) of Tetrahydrofuran (109-99-9) in F344/N Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C60560C) of Tetrahydrofuran (109-99-9) in B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Tetrahydrofuran (109-99-9) in Micronucleus Study A34612 in B6C3F1 Mice
Genetic Toxicity Evaluation of Tetrahydrofuran in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 551903
Summary Data
Genetic Toxicity Evaluation of Tetrahydrofuran in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 620162
Summary Data