U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Colchicine (64-86-8)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5024845

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Colchicine (64-86-8).
Rodent Cytogenetics
CA SCE
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative
  • View
    • Positive
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Equivocal
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Equivocal
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Equivocal
  • View
    • Positive
  • View
    • Positive
  • View
    • Positive
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative
  • View
    • Equivocal
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Not a Valid Test
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Equivocal
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative
  • View
    • Equivocal
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative
  • View
    • Positive
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Not a Valid Test
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Equivocal
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Equivocal
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Not a Valid Test
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative
  • View
    • Positive
  • View
    • Positive
  • View
    • Positive
  • View
    • Equivocal
  • View
    • Positive
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Positive
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative
  • View
    • Negative (Nonstandard Protocol)
  • View
    • Negative (Nonstandard Protocol)
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Colchicine (64-86-8).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Colchicine (64-86-8).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Colchicine (64-86-8).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. Colchicine (64-86-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TOX-45 Renal Toxicity Studies of Selected Halogenated Ethanes Administered by Gavage to F344/N Rats
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Colchicine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 628962
Summary Data

Other NTP Studies

Screen for Developmental Toxicity in Zebrafish- Study 1
Results

NTP Data Collections